In a randomized trial, the MC4R agonist setmelanotide reduced BMI and hunger in patients with acquired hypothalamic obesity. After 1 year, participants lost 36.4 lb with setmelanotide but gained 5.3…
For adults with elevated cardiometabolic risk who usually slept for at least 7 hours per night, body weight increased by 1 lb over 6 weeks when they lost 1.5 hours…
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