U.S. kindergarten vaccination rates inched down again last year and the share of children with exemptions rose to an all-time high, according to federal data posted Monday. The fraction of…
The Bacillus Calmette-Guérin (BCG) vaccine is known to induce “trained immunity,” a form of long-lasting reprogramming of innate immune responses. In a pilot study, BCG changed how immune cells behaved…
Study design and patient populations The Rural Adolescent Vaccine Enterprise (RAVE) study [22] was a five-year cluster randomized trial that utilized a stepped-wedge study design to implement and evaluate a…
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